Study of Screening, Treatment and Effective Management of Gestational Diabetes Mellitus (STEM-GDM)


To evaluate the prevalence of Gestational Diabetes Mellitus (GDM) using the new diagnostic criteria proposed by the International Association of Diabetes and Pregnancy Study Groups (IADPSG) among Peruvian women attending perinatal care and to provide objective evidence that will help improve the local guidelines for standardized GDM screening/diagnosis, effective management and treatment.


The impact of gestational diabetes mellitus (GDM) on maternal and perinatal health is well-established. GDM, defined as carbohydrate intolerance with onset or first recognition during pregnancy, has been associated with various adverse maternal and fetal outcomes. The initial criteria for its diagnosis were established more than 40 years ago. These selective criteria were derived from non-pregnant individuals and not necessarily to identify pregnancies with increased risk for adverse perinatal outcome. Before 2010, recommendations were a two stage screening that is cost prohibitive in many low income settings. In 2010, the IADPSG recommended universal early testing in populations with a high prevalence of type 2 diabetes.

Study Design and Setting

A prospective cohort study involving blood collection for assessment of glucose tolerance and other biological markers, brief physical examination for collection of vital signs, and questionnaire for collection of sociodemographic information, depression, stress, sleep disorders and other lifestyle factors, and management of identified GDM cases by trained doctors and a nutritionist.

Key Study Personnel

Dr. Michelle Williams, Principal Investigator
Dr. Miguel Angel Luque Fernandez, Co-Investigator
Dr. Bizu Gelaye, Co-Investigator
Dr. Sixto Sanchez, Co-Investigator
Dr. Gloria Larrabure, Co-Investigator
Dr. Percy Pacora, Co-Investigator
Ms. Vicky Montoya, Nutritionist
Ms. Mirtha Grande, Project Coordinator